Sugar-coated nanoparticles target macrophages, reverse pulmonary fibrosis: Nanoparticle platform delivers a nucleotide that blocks production of scar-promoting protein

Scientists have developed a treatment for pulmonary fibrosis by using nanoparticles coated in mannose — a type of sugar — to stop a population of lung cells called macrophages that contribute to lung tissue scarring. The cell-targeting method holds promise for preventing this severe lung scarring disease, which can result in life-threatening complications like shortness of breath.

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