To treat or to tolerate (pathogens), that is the question: Research in frog embryos identifies drugs that could be repurposed to treat infections in mammals by inducing tolerance to pathogens

Scientists have used Xenopus laevis tadpoles to tease out the genetic and biological mechanisms that enhance disease tolerance, and have identified drugs that can keep the tadpoles alive even in the presence of lethal bacteria. Many of the same mechanisms are also found in mammals, suggesting that humans and other animals could one day be treated for disease by increasing their tolerance to pathogens rather than killing the pathogens themselves.

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